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Cytopoint Indications

Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.

Apoquel Indications

Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

Apoquel Important Safety Information

Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines.

For more information, please see the full Prescribing Information.

About Cytopoint®

Cytopoint has improved the lives of pet owners, veterinarians and dogs who have allergic pruritus 1,2

Long-acting injectables such as Cytopoint offer a simplified treatment routine 3


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Pet owner quality of life* more than doubled after 1 week with Cytopoint2

Cytopoint provides lasting control of allergic pruritus4

Long-acting injectables such as Cytopoint may offer a simplified treatment routine for pet owners3

Research indicates that simplified treatment routines may lower pet owner anxiety5

Reduction in a dog's allergic pruritus directly correlated with a significant improvement in pet owner quality of life2*

*The Canine Dermatitis Quality of Life (QoL) instrument measured dog QoL, dog owner QoL and treatment satisfaction.2


How Cytopoint Works

Cytopoint is the first and only caninized monoclonal antibody (mAb) treatment for dogs that specifically targets and neutralizes canine IL-31, with minimal impact on normal immune functions6,7

Together, we continue to change the way we approach allergic pruritus

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When to reach for Cytopoint or Apoquel® (oclacitinib tablet)

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One injection. Lasting relief.

  • Begins to relieve allergic pruritus within 24 hours and lasts for 4 to 8 weeks8
  • Dogs of all ages
  • Lifelong disease management
  • Management of allergic pruritic flares
  • Owners seeking nondrug therapy
  • Dogs who are difficult to pill or cases in which owner compliance is a concern
  • For dogs with comorbidities

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First choice for fast relief

  • Rapid allergic itch relief begins within 4 hours9
  • Significant reduction of inflammation due to allergic dermatitis9
  • Start-and-stop itch control that can be used during diagnostic trials10
  • Management of allergic pruritic flares
  • Short- and long-term management of allergic itch
  • For dogs at least 12 months of age

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Provide individualized treatment of allergic and atopic dermatitis with 2 trusted treatment options

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References: 1. Data on file, Quality of Life Outcomes Research, 2018, Zoetis Inc. 2. Data on file, Apoquel®/Cytopoint® Vet Tracker, Wave 16, 2021, Zoetis Inc. 3. Data on file, Apoquel®/Cytopoint® Pet Tracker, Wave 10, 2021, Zoetis Inc. 4. Souza CP, Rosychuk RAW, Contreras ET, et al. A retrospective analysis of the use of lokivetmab in the management of allergic pruritus in a referral population of 135 dogs in the western USA. Vet Dermatol. 2018;29(6):489-e164. doi:10.1111/vde.12682. 5. Spitznagel MB, Cox MD, Jacobson DM, et al. Assessment of caregiver burden and associations with psychosocial function, veterinary service use, and factors related to treatment plan adherence among owners of dogs and cats. J Am Vet Med Assoc. 2019;254(1):124-132. doi:10.2460/javma.254.1.124. 6. Data on file, Press Release, September 2016, Zoetis Inc. 7. Gonzales AJ, Humphrey WR, Messamore JE, et al. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Vet Dermatol. 2013;24(1):48-e12. doi:10.1111/j.1365-3164.2012.01098.x. 8. Data on file, Study No. C863R-US-12-018, 2014, Zoetis Inc. 9. Gadeyne C, Little P, King VL, et al. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25(6):512-e86. doi:10.1111/vde.12166. 10. Aleo MM, Galvan EA, Fleck JT, et al. Effects of oclacitinib and prednisolone on skin test sensitivity [abstract]. Vet Dermatol. 2013;24(3):297.

Cytopoint Indications

Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.

Apoquel Indications

Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

Apoquel Important Safety Information

Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines.

For more information, please see the full Prescribing Information.

Cytopoint Indications

Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.

Apoquel Indications

Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

Apoquel Important Safety Information

Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines.

For more information, please see the full Prescribing Information.